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4.
JPEN J Parenter Enteral Nutr ; 39(2): 154-62, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24096266

RESUMO

BACKGROUND: Enteral nutrition (EN) is controversial in patients with circulatory compromise. This study assesses the feasibility and safety of EN given early after cardiac surgery in patients with hemodynamic failure. METHODS: Prospective observational study conducted in a surgical intensive care unit (ICU) of a tertiary hospital over 17 months. INCLUSION CRITERIA: Cardiac surgery patients with hemodynamic failure (dependence on 2 or more vasoactive drugs and/or mechanical circulatory support) requiring more than 24 hours of mechanical ventilation. Variables Examined: Descriptive data, daily hemodynamic data, and variables related to the efficacy and safety of EN. EN was performed according to our EN protocol. RESULTS: Of 642 patients admitted to the ICU, 37 (5.8%) met the inclusion criteria. Of these, 11 (29.7%) required mechanical circulatory support, and 25 (68.0%) met the criteria for early multiorgan dysfunction. Mortality was 13.5%. Mean EN duration was 12.3 days (95% confidence interval [CI], 9.6-15.0). The mean EN diet volume delivered/patient/d was 1199 mL (95% CI, 1118.7-1278.8), and mean EN energy delivered/patient/d was 1228.4 kcal (95% CI, 1145.8-1311). The set energy target was achieved in 15 patients (40.4%). The most common EN-related complication was constipation. No case of mesenteric ischemia was detected. CONCLUSIONS: Our findings indicate that early EN is feasible in this type of patients and not associated with serious complications. However, it is difficult to attain an appropriate energy target by EN alone. These observations point to a need for monitoring of daily energy delivery and balance, as well as careful monitoring of warning signs of intestinal ischemia.


Assuntos
Procedimentos Cirúrgicos Cardíacos/efeitos adversos , Cuidados Críticos/métodos , Nutrição Enteral/métodos , Cardiopatias/complicações , Hemodinâmica , Respiração Artificial/enfermagem , Idoso , Constipação Intestinal/etiologia , Estado Terminal/enfermagem , Ingestão de Energia , Nutrição Enteral/efeitos adversos , Feminino , Cardiopatias/cirurgia , Humanos , Unidades de Terapia Intensiva , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Respiração Artificial/efeitos adversos , Resultado do Tratamento
6.
JPEN J Parenter Enteral Nutr ; 37(2): 281-4, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-22750804

RESUMO

BACKGROUND: Despite its benefits, early enteral nutrition (EN) is considered controversial in critically ill patients with severe hemodynamic failure. OBJECTIVE: To evaluate the tolerance and safety of early EN in a consecutive group of patients receiving venoarterial (VA) extracorporeal membrane oxygenation (ECMO) for severe hemodynamic failure. MATERIALS AND METHODS: Prospective observational study performed in a cardiac surgical intensive care unit (ICU) during a 1-year period. All adult patients receiving VA ECMO for severe hemodynamic failure unresponsive to conventional therapies were included. Nutrition support was provided during the study period following the established ICU nutrition protocol. Energy target was 25 kcal/kg, to be reached over 4 days. Nutrition tolerance was defined as the ratio of delivered nutrition to target nutrition, expressed as a percentage. Special interest was made to detect possible adverse effects attributable to EN. The authors performed a descriptive statistical analysis. RESULTS: Of 553 patients admitted in the cardiac surgical ICU during the study period, 7 were treated with ECMO. EN was the only nutrition source. More than 70% nutrition tolerance was achieved within the first week in all cases. No serious adverse events that could be attributable to EN were noted. CONCLUSION: The present study shows that, under proper medical supervision, early EN is possible and safe in patients with severe hemodynamic failure receiving VA ECMO. No serious adverse events were attributable to EN. More studies are warranted to confirm these findings.


Assuntos
Estado Terminal/terapia , Nutrição Enteral/métodos , Oxigenação por Membrana Extracorpórea , Adulto , Procedimentos Cirúrgicos Cardíacos , Ingestão de Energia , Nutrição Enteral/efeitos adversos , Feminino , Cardiopatias/complicações , Cardiopatias/cirurgia , Hemodinâmica , Humanos , Unidades de Terapia Intensiva , Masculino , Pessoa de Meia-Idade , Observação , Estudos Prospectivos , Insuficiência Respiratória/etiologia , Insuficiência Respiratória/cirurgia , Adulto Jovem
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